Advancing Laboratory Efficiency: The Evolution of the Multi-Tier™ Plate System

Ever since the introduction of the autosampler, which revolutionized combinatorial chemistry, there has been a relentless drive to enhance the speed and efficiency of sample testing. Laboratories have continuously sought ways to minimize sample amounts and reduce experimental costs, all while maintaining high throughput and accuracy. One of the key milestones in this journey was the adoption of the 12x32mm vial as the primary vessel for sample storage prior to testing.

Recognizing the industry's need for high-quality vials, seals, and closures, J.G. Finneran Associates played a crucial role in supplying these essential components. As the demand for even more efficient solutions grew, the introduction of the 96-well plate brought a significant advancement. With its compact 85mm x 127mm "footprint," it provided a streamlined approach to high-throughput sample processing. However, Jerry Finneran saw an opportunity to further refine the sample handling process by integrating the precision of glass vials into the 96-well plate environment.

The Multi-Tier™ Plate System: A Game Changer in Sample Handling

The result was the development of the patented Multi-Tier™ Plate system, a modular, reusable innovation designed to optimize laboratory workflows. This system features a base plate that accommodates a variety of vial sizes, including 0.5mL, 1.0mL, 1.5mL, 2.0mL, and 2.5mL conical glass, flat-bottom, and polypropylene vials. The vented design ensures uniform heating and cooling when submerged in a water bath, enhancing consistency.

One of the stand-out features of the Multi-Tier™ Plate system is its ability to securely fit vials in the base plate, allowing compatibility with shaker and vortex mixers during sample preparation. Additionally, the cover locks the liner in place, preventing vial pullout, while the prescored PTFE/Silicone/PTFE liner facilitates easy needle penetration. The molded PTFE/Silicone liner further enhances usability by securely locking into each vial, resealing after multiple injections to minimize solvent evaporation and prevent cross-contamination.

Advantages of Isolating Samples in Glass Vials

Compared to traditional 96-well microplates, the Multi-Tier™ Plate system provides distinct advantages through its use of individual glass vials for sample containment. Glass vials offer superior chemical resistance, preventing potential leaching or contamination that could compromise sample integrity. The ability to isolate samples in separate vials also reduces the risk of cross-contamination, where sample evaporation and splashing can occur. Furthermore, the adjustable spacer system ensures optimal vial positioning, accommodating different vial sizes while maintaining sample stability.

Another key benefit is compatibility with all autosamplers and robotic systems, ensuring seamless integration into existing laboratory workflows. The modular and reusable nature of the Multi-Tier™ Plate system significantly reduces waste and long-term costs, making it an eco-friendly and cost-effective choice for high-throughput laboratories.

Why Choose the Multi-Tier™ Plate System Over Standard 96-Well Microplates?

• Providing enhanced chemical compatibility using glass vials.
• Reducing cross-contamination risk with individually sealed and resealable vial liners or plugs.
• Offering precise temperature control with its vented base plate design.
• Supporting a variety of vial sizes with an adaptable spacer system.
• Enabling easy sample retrieval and reusability, lowering consumable costs.
• Ensuring compatibility with high-throughput robotic and autosampler systems.

Conclusion

The Multi-Tier™ Plate system represents a significant advancement in sample processing, combining the efficiency of the 96-well plate format with the reliability and precision of individual glass vials. By reducing contamination risks, improving sample stability, and offering unparalleled adaptability, this system is an ideal choice for laboratories seeking to optimize their workflows while maintaining high-quality analytical results. As laboratory needs continue to evolve, innovations like the Multi-Tier™ Plate system will remain essential in pushing the boundaries of efficiency and reliability in scientific research.